From the agent endpoint machine (the unix/windows machine) what are the results of the following commands?
ping bigfixserver.company.com nslookup bigfixserver.company.com traceroute bigfixserver.comany.com
Is the BigFix server reachable DNS resolvable on the network from the agent machine?
What is the __RelayServer1 client setting set to?
It should be in the form of http://bigfixserver.company.com:52311/bfmirror/downloads
Is it a fully qualified domain name that is entered here? A name that is DNS resolvable?
If you replace the name with the IP address of the BigFix server, and restart the BESClient service, does that resolve the issue? For example:
Also, have you set the following client setting in the __RelaySelect_Automatic setting equal to 0 in the in the registry setting.