@Gujumax, it’s absolutely possible. To start you’ll want to install and get familiar with the Server Automation REST API. Once the has been installed, you can create a script to be scheduled and executed using the provided service account and begin start testing your process.
When I was a BigFix customer, I developed a process leveraging BigFix content and Server Automation to uninstall all INFRA and related software/config from the in-store servers and then rebuild the software after they’ve been renamed for a division migration as hostnames had division artifacts.
There were two automation plans with dozens of steps. In that case, the SA REST integration was with the enterprise helpdesk as it had an existing service account configuration with BigFix that had sufficient privileges to execute the division migration process.
Please note that the SA REST API is completely separate from the BigFix platform REST API that’s installed by default. There should be a fixlet in the “Server Automation” site to deploy the SA REST API to an available Windows server OS BigFix infrastructure server.
Hope this helps.