The property “Office 365 - Office 2016 Client Architecture” depends on a ClickToRun install of Office; while this would definitely be useful for an all-Office 365 shop, it wouldn’t work in my environment as we still have older products.
That being said, I am seeing good results for that relevance based on a quick check through BigFix Query in my environment with O365, similar to AlexaVonTess’ comment.
You’ll need to verify what your requirements are in terms of scope of Office versions, it seems.