(I suppose I should say, I don’t know for sure whether that KB is actually the May 2022 update or not; I was checking it’s release date but it’s been modified a few times since its release.)
Both Domain Controllers, and CA Servers should have the May 2022 update installed (in fact so should every Windows server).
But the registry entries to enable Enforcement or Compatibility modes in Fixlets 623 and 624 only apply to Domain Controllers. Those Fixlets don’t install the update, they just manage the registry entries.