Yikes.
I would recommend to open a PMR right away.
A few things you may want to try to clean the endpoint. (1) uninstall agent, delete local folder for agent and remove the bigfix section of the registry from HKLM\Software\WOW6432NODE\BigFix\ (2) Then reinstall the agent.
You also may want to check that the masthead is not mangled (re:edited) in any way, check the hash of the masthead.
But, I would still open a PMR ASAP.
-jgo
Read about how to register and file a PMR / SR here: IBM Products
I’ve seen this occur a couple of times and we managed to trace the cause down to a missing/corrupt C runtime library. Using a dependency walker we loaded the libbescrypto.dll file and it highlighted the file causing the issue. I believe our case were due to a corrupted file system that affected the WinSxs side-by-side store.