One thing to remember is the following:
On 32-bit windows the system32 folder is the x86 system folder.
On 64-bit windows the system32 folder is the x64 system folder and syswow64 is the x86 system folder.
You can remember that Syswow64 stands for system, Windows on windows 64 (I.e. Windows x86 on x64).
Because besclient and QnA are native 32-bit applications windows redirects file reads to system32 (the 64-bit folder) to syswow64 automatically. Using x64 folders in relevance essentially tells the client to ignore the redirection.