This is possible, but not in an officially IBM supported way. Several years ago I took the original premise of the Local Admin Bigfix Labs tool and adapted it for precisely this purpose. My use case is to dynamically target machines that may or may not yet exist with certain secure bits of information such as passwords. I’ve targeted thousands of machines dynamically for a while now. I just wish IBM would incorporate the use case into the official product.
See this post for more details as well as the last post in this thread.