(imported topic written by bhorta191)
I will post more details (when I get to work)
We use Bigfix successfully here. 103,000 desktops and over 340 individual locations (private WAN, 340 router)
and one BES server (1 raid with several 10K drives)
(imported comment written by bhorta191)
108,000 desktops. And Bigfix is still the Gold Standard of customer support 
(imported comment written by StacyLee)
how many relays?